Kessler researchers correlate cognitive fatigue after TBI with activation of the caudate

(Kessler Foundation) ‘These results are consistent with findings in our related research in the multiple sclerosis (MS) population,’ said Dr. Wylie, the lead author, ‘which suggests that the TBI and MS populations share a mechanism for cognitive fatigue.’ This has important implications for the development of effective treatments. ‘This study points to the caudate nucleus as a likely target for clinical interventions to alleviate fatigue,’ explained Dr. Wylie, who is associate director of Neuroscience Research and the Rocco Ortenzio Neuroimaging Center at Kessler Foundation.