(Elsevier) There is a broad collection of anomalies now known as congenital Zika syndrome (CZS). Some of the most serious are ophthalmologic. Two papers published in the Journal of the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) evaluated visual function among infants with suspected and confirmed CZS. Both studies found that while about 40 percent of patients had ocular abnormalities, 100 percent of children tested had visual impairment. Thus, cortical visual impairment might be the most common cause of blindness among children with CZS.