Genetic basis of quantitative traits and diseases in Japanese


Researchers presented one of the largest non-European genome-wide association study (GWAS) of quantitative biological traits to date, identifying 1,407 trait-associated loci for 58 traits in 162,255 Japanese individuals. By incorporating the additional GWAS results of the 32 complex diseases and traits in Japanese, they further identified numerous loci that control more than one trait, together with the wide-ranging genetic correlations and distinct cell-type specificity among the quantitative traits and diseases.