CU researchers identify potential treatment for diastolic dysfunction in heart failure

(University of Colorado Anschutz Medical Campus) Researchers at the University of Colorado School of Medicine have identified a potential treatment target for patients with a common type of heart failure. In a study published in the Feb. 7 issue of the journal Science Translational Medicine, the researchers tested the effect of an investigational drug called givinostat in treating diastolic dysfunction, which is a heart relaxation abnormality that contributes to heart failure with preserved ejection fraction (HFpEF).